Structure of PDB 4r29 Chain A

Receptor sequence
>4r29A (length=199) Species: 83334 (Escherichia coli O157:H7) [Search protein sequence]
HVVKNIYPEIKHDYFNESPNIYDKKYISGITRVAELKQEEFVNEKARRFS
YMKTMYSVCPEAFEPISRNEASTPEGSWLTVISGKRPMGQFSVDSLYNPD
LHALCELPDICCKIFPKENNDFLYIVVVYRNDSPLGEQRANRFIELYNIK
RDIMQELNYALPELKAVKSEMIIAREMGEIFSYMPGEIDSYMKYINNKL
3D structure
PDB4r29 Structure and Specificity of the Bacterial Cysteine Methyltransferase Effector NleE Suggests a Novel Substrate in Human DNA Repair Pathway.
ChainA
Resolution2.31 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAM A R89 A92 S98 R107 G110 Q111 E191 A195 M198 F202 Y204 E208 Y212 R68 A71 S77 R86 G89 Q90 E170 A174 M177 F181 Y183 E187 Y191
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0090729 toxin activity
Biological Process
GO:0032259 methylation
GO:0035821 modulation of process of another organism
Cellular Component
GO:0005576 extracellular region
GO:0042025 host cell nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4r29, PDBe:4r29, PDBj:4r29
PDBsum4r29
PubMed25412445
UniProtQ7DBA6|NLEE_ECO57 Cysteine S-methyltransferase NleE (Gene Name=nleE)

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