Structure of PDB 4qyz Chain A

Receptor sequence
>4qyzA (length=468) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MNLLIDNWIPVRPRNGGKVQIINLQSLYCSRDQWRLSLPRDDMELAALAL
LVCIGQIIAPAKDDVEFRHRIMNPLTEDEFQQLIAPWIDMFYLNHAEHPF
MQTKGVKANDVTPMEKLLAEALCGGCTAIALFNQANQAPGFGGGFKSGLR
GGTPVTTFVRGIDLRSTVLLNVLTLPRLQKQFPNESHTENQPTWIKPIKS
NESIPASSIGFVRGLFWQPAHIELCDPIGIGKCSCCGQESNLRYTGFLKE
KFTFTVNGLWPHPHSPCLVTVKKGEVEEKFLAFTTSAPSWTQISRVVVDK
INGNRVAAVVNQFRNIAPQSPLELIMGGYRLERRHDVLMFNQGWQQYGNV
INEIVTVGLGYKTALRKALYTFAEGFKNKDFKGAGVSVHETAERHFYRQS
ELLIPDVLANVNFSQADEVIADLRDKLHQLCEMLFNQSVAPYAHHPKLIS
TLALARATLYKHLRELKP
3D structure
PDB4qyz Structural biology. Crystal structure of a CRISPR RNA-guided surveillance complex bound to a ssDNA target.
ChainA
Resolution3.0303 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A K409 H472 K382 H445
BS02 ZN A C140 C143 C250 C253 C123 C126 C233 C236
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0051607 defense response to virus
GO:0099048 CRISPR-cas system
Cellular Component
GO:0032991 protein-containing complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4qyz, PDBe:4qyz, PDBj:4qyz
PDBsum4qyz
PubMed25123481
UniProtQ46901|CSE1_ECOLI CRISPR system Cascade subunit CasA (Gene Name=casA)

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