Structure of PDB 4qxk Chain A

Receptor sequence
>4qxkA (length=127) Species: 9606 (Homo sapiens) [Search protein sequence]
KHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDT
FFIISKGTVNVTREDSPDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAE
AVTCLVIDRDSFKHLIGGLDDVSNKAY
3D structure
PDB4qxk Neutron Diffraction Reveals Hydrogen Bonds Critical for cGMP-Selective Activation: Insights for cGMP-Dependent Protein Kinase Agonist Design.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.12: cGMP-dependent protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PCG A L296 R297 F305 G306 E307 K308 A309 R316 T317 Y351 L72 R73 F81 G82 E83 K84 A85 R92 T93 Y127
External links
PDB RCSB:4qxk, PDBe:4qxk, PDBj:4qxk
PDBsum4qxk
PubMed25271401
UniProtQ13976|KGP1_HUMAN cGMP-dependent protein kinase 1 (Gene Name=PRKG1)

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