Structure of PDB 4qvf Chain A

Receptor sequence
>4qvfA (length=141) Species: 9606 (Homo sapiens) [Search protein sequence]
SQSNRELVVDFLSYKLSQKGYSWSQFSDVAVKQALREAGDEFELRYRRAF
SDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESV
DKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG
3D structure
PDB4qvf Bh3 induced conformational changes in Bcl-Xl revealed by crystal structure and comparative analysis.
ChainA
Resolution1.531 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A E96 F97 R100 Y101 F105 L108 Q111 S122 V126 E129 L130 N136 G138 R139 Y195 E41 F42 R45 Y46 F50 L53 Q56 S67 V71 E74 L75 N81 G83 R84 Y140
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:4qvf, PDBe:4qvf, PDBj:4qvf
PDBsum4qvf
PubMed25907960
UniProtQ07817|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)

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