Structure of PDB 4qqq Chain A

Receptor sequence
>4qqqA (length=483) Species: 1313 (Streptococcus pneumoniae) [Search protein sequence]
HHHSSGLVPRGSHMANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGN
QLPDEFVVIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNP
TLLAVDRAPMTYSIDLPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQD
YGQVNNVPARMQYEKITAHSMEQLKVKFGSDFEKTGNSLDIDFNSVHSGE
KQIQIVNFKQIYYTVSVDAVKNPGDVFQDTVTVEDLKQRGISAERPLVYI
SSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQTEWKQILDNTEV
KAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFLR
DNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQ
GKEVLTPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWR
TVYEKTDLPLVRKRTISIWGTTLYPQVEDKVEN
3D structure
PDB4qqq Crystal structure of pneumolysin from Streptococcus pneumoniae, in complex with mannose as a component of cell membrane
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN A T405 A406 H407 T418 A419 H420
BS02 MAN A V372 D403 C428 W435 W436 V385 D416 C441 W448 W449
Gene Ontology
Molecular Function
GO:0008289 lipid binding
GO:0015485 cholesterol binding
GO:0090729 toxin activity
Biological Process
GO:0031640 killing of cells of another organism
GO:0035821 modulation of process of another organism
Cellular Component
GO:0005576 extracellular region
GO:0016020 membrane
GO:0020002 host cell plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4qqq, PDBe:4qqq, PDBj:4qqq
PDBsum4qqq
PubMed
UniProtQ2XU26

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