Structure of PDB 4qn3 Chain A

Receptor sequence
>4qn3A (length=390) Species: 352589 (Influenza A virus (A/mallard/ALB/196/1996(H10N7))) [Search protein sequence]
NYLMLNKSLCKVEGWVVVAKDNAIRFGESEQIIVTREPYVSCDPLGCKMY
ALHQGTTIRNKHSNGTIHDRTAFRGLISTPLGSPPIVSNSDFLCVGWSST
SCHDGIGRMTICVQGNNDNATATVYYDRRLTTTIKTWAGNILRTQESECV
CHNGTCVVIMTDGSASSQAYTKVLYFHKGLVIKEEALKGSARHIEECSCY
GHNSKVTCVCRDNWQGANRPVIEIDMNAMEHTSQYLCTGVLTDTSRPSDK
SIGDCNNPITGSPGAPGVKGFGFLDSGNTWLGRTISPRSRSGFEMLKIPN
AGTDPNSRITERQEIVDNNNWSGYSGSFIDYWDESSECYNPCFYVELIRG
RPEEAKYVWWTSNSLVALCGSPVPVGSGSFPDGAQIQYFS
3D structure
PDB4qn3 Structure of influenza virus N7: the last piece of the neuraminidase "jigsaw" puzzle.
ChainA
Resolution2.092 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D69 E196 R211 R290 Y324
Catalytic site (residue number reindexed from 1) D69 E196 R211 R290 Y324
Enzyme Commision number 3.2.1.18: exo-alpha-sialidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D212 G216 D243 P266 D212 G216 D243 P266
Gene Ontology
Molecular Function
GO:0004308 exo-alpha-sialidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
Cellular Component
GO:0016020 membrane
GO:0033644 host cell membrane
GO:0055036 virion membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4qn3, PDBe:4qn3, PDBj:4qn3
PDBsum4qn3
PubMed24899180
UniProtQ20R18

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