Structure of PDB 4qmg Chain A

Receptor sequence
>4qmgA (length=311) Species: 9606 (Homo sapiens) [Search protein sequence]
PTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAAT
QPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGK
DTNGENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSE
GNGSHTIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDY
YLVTVMLSGIKCPTFRRTPEPFAAEAKFFTESRLLQRDVQIILESCHNQN
ILGTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERR
LRIWRDYVAPT
3D structure
PDB4qmg Structural Insights into the Tumor-Promoting Function of the MTDH-SND1 Complex.
ChainA
Resolution2.701 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.31.1: micrococcal nuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A P39 G42 P43 R87 K93 F244 A246 E247 F250 S254 R255 L256 R259 D260 H279 N281 L287 R324 P23 G26 P27 R71 K77 F222 A224 E225 F228 S232 R233 L234 R237 D238 H257 N259 L265 R302
BS02 peptide A R140 A141 R124 A125
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004518 nuclease activity

View graph for
Molecular Function
External links
PDB RCSB:4qmg, PDBe:4qmg, PDBj:4qmg
PDBsum4qmg
PubMed25242325
UniProtQ7KZF4|SND1_HUMAN Staphylococcal nuclease domain-containing protein 1 (Gene Name=SND1)

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