Structure of PDB 4qf9 Chain A

Receptor sequence
>4qf9A (length=250) Species: 10116 (Rattus norvegicus) [Search protein sequence]
TLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFLYDVK
LVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKP
FMTLGISILYRKGTPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTY
EKMWAFMSSRQQSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNL
TQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGN
3D structure
PDB4qf9 Binding Mode of an alpha-Amino Acid-Linked Quinoxaline-2,3-dione Analogue at Glutamate Receptor Subtype GluK1.
ChainA
Resolution2.28 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 35K A Y16 Y61 P88 L89 T90 R95 T192 S193 Y216 Y12 Y57 P84 L85 T86 R91 T188 S189 Y212 MOAD: Ki=37.1uM
PDBbind-CN: -logKd/Ki=4.43,Ki=37.1uM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:4qf9, PDBe:4qf9, PDBj:4qf9
PDBsum4qf9
PubMed25856736
UniProtP22756|GRIK1_RAT Glutamate receptor ionotropic, kainate 1 (Gene Name=Grik1)

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