Structure of PDB 4qdi Chain A

Receptor sequence
>4qdiA (length=457) Species: 557600 (Acinetobacter baumannii AB307-0294) [Search protein sequence]
VPLEPWTAQQLQQATQGYWHKDQIPQTEIKRILTDSRHAESGDAFLALKG
ERFDAHNFVAQVVANGCQVAIVERPIDAEIAQLVVADTRLALGQLGAYRR
EQNAQLKVIALTGSSGKTTTKEMLGSILSRLAPTLITRGNLNNDLGVPMM
LLELRKEHQYAVMELGANHQGEIDYTSKIVQPHVAGILNIGTAHLGEFGG
RDGICRAKSEIYRHILPQGVAIVPQQDDFTAEIREAAKSHQIMSFGEGGD
VFATEIELLPQSANFQLHTPQGSSFVRLPFAGEHNVQNATAAVAFALALG
VSLEDIVKGLEQAQGAKGRLNFIQKAPHLFIDDTYNANPTSMRAAAQVLL
QQNGIKVMVMGDIGELGDSSWQEHHDLGRDLAELPLDHIVAVGQFASAAL
EGAGLHSTKLKAFQTQAEALPFLINLIQTHQPQSMSFLFKGSRFTHMETL
MADLMEK
3D structure
PDB4qdi ATP-binding mode including a carbamoylated lysine and two Mg(2+) ions, and substrate-binding mode in Acinetobacter baumannii MurF
ChainA
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K125 T126 N148 E172 H202
Catalytic site (residue number reindexed from 1) K117 T118 N140 E164 H194
Enzyme Commision number 6.3.2.10: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A S123 G124 K125 T126 T127 H292 N296 R327 Y343 N344 S115 G116 K117 T118 T119 H284 N288 R319 Y335 N336
BS02 UDP A T42 F61 L153 T34 F53 L145
BS03 MG A T126 E172 T118 E164
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008766 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
GO:0016874 ligase activity
GO:0016881 acid-amino acid ligase activity
GO:0046872 metal ion binding
GO:0047480 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Biological Process
GO:0008360 regulation of cell shape
GO:0009058 biosynthetic process
GO:0009252 peptidoglycan biosynthetic process
GO:0051301 cell division
GO:0071555 cell wall organization
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4qdi, PDBe:4qdi, PDBj:4qdi
PDBsum4qdi
PubMed24978312
UniProtA0A0J9X1Z8

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