Structure of PDB 4q7f Chain A

Receptor sequence

>4q7fA (length=510) Species: 93062 (Staphylococcus aureus subsp. aureus COL)

SNIAFYVVSDVHGYIFPTDFTSRNQYQPMGLLLANHVIEQDRRQYDQSFK
IDNGDFLQGSPFCNYLIAHSGSSQPLVDFYNRMAFDFGTLGNHEFNYGLP
YLKDTLRRLNYPVLCANIYENDSTLTDNGVKYFQVGDQTVGVIGLTTQFI
PHWEQPEHIQSLTFHSAFEILQQYLPEMKRHADIIVVCYHGGFEKDLESG
TPTEVLTGENEGYAMLEAFSKDIDIFITGHQHRQIAERFKQTAVIQPGTR
GTTVGRVVLSTDEYENLSVESCELLPVIDDSTFTIDEDDQHLRKQLEDWL
DYEITTLPYDMTINHAFEARVAPHPFTNFMNYALLEKSDADVACTALFDS
ASGFKQVVTMRDVINNYPFPNTFKVLAVSGAKLKEAIERSAEYFDVKNDE
VSVSADFLEPKPQHFNYDIYGGVSYTIHVGRPKGQRVSNMMIQGHAVDLK
QTYTICVNNYRAVGGGQYDMYIDAPVVKDIQVEGAQLLIDFLSNNNLMRI
PQVVDFKVEK

3D structure

• PDB: 4q7f 1.98 Angstrom Crystal Structure of Putative 5'-Nucleotidase from Staphylococcus aureus in complex with Adenosine.
• Chain: A
• Resolution: 1.98 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): N93 H94 N97
• Catalytic site (residue number reindexed from 1): N92 H93 N96

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MG	A	D56 N93 H191 H231	D55 N92 H190 H230
BS02	MN	A	D11 H13 D56 H233	D10 H12 D55 H232
BS03	3D1	A	H94 W154 F370 N372 F416 Y461	H93 W153 F369 N371 F415 Y460

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0008252 nucleotidase activity
• GO:0016787 hydrolase activity
• GO:0016788 hydrolase activity, acting on ester bonds
• GO:0046872 metal ion binding

Biological Process

• GO:0009166 nucleotide catabolic process

Cellular Component

• GO:0030288 outer membrane-bounded periplasmic space

External links

• PDB: RCSB:4q7f, PDBe:4q7f, PDBj:4q7f
• PDBsum: 4q7f
• UniProt: Q2G1L5