Structure of PDB 4q5p Chain A

Receptor sequence

>4q5pA (length=106) Species: 4932 (Saccharomyces cerevisiae)

FKAGSAKKGATLFKTRCLQCHTVEKGGPHKVGPNLHGIFGRHSGQAEGYS
YTDANIKKNVLWDENNMSEYLTNPAKYIPGCGMAFGGLKKEKDRNDLITY
LKKASE

3D structure

• PDB: 4q5p A Compact Structure of Cytochrome c Trapped in a Lysine-Ligated State: Loop Refolding and Functional Implications of a Conformational Switch.
• Chain: A
• Resolution: 1.87 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEM	A	R13 C14 Q16 C17 H18 V28 I35 S40 Y48 T49 D50 M64 Y67 L68 K73 I75 L94	R16 C17 Q19 C20 H21 V31 I38 S43 Y51 T52 D53 M67 Y70 L71 K76 I78 L97

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0009055 electron transfer activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding
• GO:1901612 cardiolipin binding

Biological Process

• GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
• GO:0006123 mitochondrial electron transport, cytochrome c to oxygen

Cellular Component

• GO:0005739 mitochondrion
• GO:0005758 mitochondrial intermembrane space

External links

• PDB: RCSB:4q5p, PDBe:4q5p, PDBj:4q5p
• PDBsum: 4q5p
• PubMed: 26038984
• UniProt: P00044|CYC1_YEAST Cytochrome c isoform 1 (Gene Name=CYC1)