Structure of PDB 4q5j Chain A

Receptor sequence
>4q5jA (length=298) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
DLEVLFQGPHMAFEKPLRKLTFADLLQATNGFHNDSLIGSGGFGDVYKAI
LKDGSAVAIKKLIHVSDREFMAEMETIGKIKHRNLVPLLGYCKVGDERLL
VYEFMKYGSLEDVLKLNWSTRRKIAIGSARGLAFLHHNCSPHIIHRDMKS
SNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFR
CSTKGDVYSYGVVLLELLTGKRPTDSPDFGDNNLVGWVKQHAKLRISDVF
DPELMKEDPALEIELLQHLKVAVACLDDRAWRRPTMVQVMAMFKEIQA
3D structure
PDB4q5j Structural insights into the negative regulation of BRI1 signaling by BRI1-interacting protein BKI1.
ChainA
Resolution2.772 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D1009 K1011 S1013 N1014 D1027 M1037 T1049
Catalytic site (residue number reindexed from 1) D147 K149 S151 N152 D165 M175 T187
Enzyme Commision number 2.7.10.1: receptor protein-tyrosine kinase.
2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K1101 K1105 L1128 V1135 D1139 D1140 K239 K243 L266 V273 D277 D278
BS02 ANP A G892 G893 A909 F958 M959 S963 D966 K1011 N1014 L1016 D1027 G41 G42 A58 F104 M105 S109 D112 K149 N152 L154 D165
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4q5j, PDBe:4q5j, PDBj:4q5j
PDBsum4q5j
PubMed25331450
UniProtO22476|BRI1_ARATH Protein BRASSINOSTEROID INSENSITIVE 1 (Gene Name=BRI1)

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