Structure of PDB 4q4f Chain A

Receptor sequence
>4q4fA (length=394) Species: 9606 (Homo sapiens) [Search protein sequence]
IEKKIVLRNGTEAFDSWEKPPLPVYTQFYFFNVTNPEEILRGETPRVEEV
GPYTYRELRNKANIQFGDNGTTISAVSNKAYVFERDQSVGDPKIDLIRTL
NIPVLTVIEWSQVHFLREIIEAMLKAYQQKLFVTHTVDELLWGYKDEILS
LIHVFRPDISPYFGLFYEKNGTNDGDYVFLTGEDSYLNFTKIVEWNGKTS
LDWWITDKCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDYES
VQGLPAFRYKVPAEILANTSDNAGFCIPEGNCLGSGVLNVSICKNGAPII
MSFPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQIN
IYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMIN
3D structure
PDB4q4f Lysosome sorting of beta-glucocerebrosidase by LIMP-2 is targeted by the mannose 6-phosphate receptor.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 M6D A L152 R153 E154 L116 R117 E118
Gene Ontology
Molecular Function
GO:0005044 scavenger receptor activity
Cellular Component
GO:0005764 lysosome
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:4q4f, PDBe:4q4f, PDBj:4q4f
PDBsum4q4f
PubMed25027712
UniProtQ14108|SCRB2_HUMAN Lysosome membrane protein 2 (Gene Name=SCARB2)

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