Structure of PDB 4q24 Chain A

Receptor sequence
>4q24A (length=224) Species: 1971 (Streptomyces noursei) [Search protein sequence]
DHGMREEILGDRSRLIRQRGEHALIGICAGNSYFSQKNTVMLLQWAGQRF
ERTDVVYVDTHIDEMLIADGRSAQEAERSVKRTLKDLRRRLRRSLESVGD
HAERFRVRSLSELQETPEYRAVRERTDRAFEEDAEFATACEDMVRAVVMN
RPGDGVGISAEHLRAGLNYVLAEAPLFADSPGVFSVPSSVLCYHIDTPIT
AFLSRRETGFRAAEGQAYVVVRPQ
3D structure
PDB4q24 Unravelling the mechanism of non-ribosomal peptide synthesis by cyclodipeptide synthases.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.20: cyclo(L-leucyl-L-phenylalanyl) synthase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 XVE A G35 C37 M152 A155 N159 Y178 E182 F186 Y202 T206 G26 C28 M143 A146 N150 Y169 E173 F177 Y193 T197
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0016755 aminoacyltransferase activity
Biological Process
GO:0002780 antibacterial peptide biosynthetic process

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:4q24, PDBe:4q24, PDBj:4q24
PDBsum4q24
PubMed25284085
UniProtQ8GED7|CLPS_STRNR Cyclo(L-leucyl-L-phenylalanyl) synthase (Gene Name=albC)

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