Structure of PDB 4q0q Chain A

Receptor sequence

>4q0qA (length=249) Species: 160971 (Acinetobacter sp. DL-28)

SARTSITRREYDEWVREAAALGKALRYPITEKMVNDSAGIVFGADQYDAF
KNGMWSGEPYEAMIIFESLNEPAVDGLPTGAAPYAEYSGLCDKLMIVHPG
KFCPPHHHGRKTESYEVVLGEMEVFYSPTPSAESGVELLNFSGMPVGSPW
PEGVALPKGRESSYEKLTSYVRLRAGDPKFVMHRKHLHAFRCPPDSDVPL
VVREVSTYSHEPTEAAAGNHAPIPSWLGMHDNDFVSDAANTGRLQTAIS

3D structure

• PDB: 4q0q X-ray structure of a novel L-ribose isomerase acting on a non-natural sugar L-ribose as its ideal substrate.
• Chain: A
• Resolution: 1.93 Å

Enzymatic activity

• Enzyme Commision number: 5.3.1.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CO	A	H106 H108 E113 H188	H106 H108 E113 H188
BS02	RUU	A	I65 M95 C103 H106 H108 K111 E113 H188 E204 E211	I65 M95 C103 H106 H108 K111 E113 H188 E204 E211
BS03	RUU	A	N35 S37 A38 I65 F66 E67 T213	N35 S37 A38 I65 F66 E67 T213
BS04	QDK	A	M33 E67 S68 L69 N70	M33 E67 S68 L69 N70
BS05	RUU	A	Y11 D12 R16 V34 N35 D36	Y11 D12 R16 V34 N35 D36
BS06	RUU	A	R9 R16	R9 R16
BS07	RUU	A	W150 Y164 E165	W150 Y164 E165
BS08	RUU	A	T129 K166 L187	T129 K166 L187
BS09	RUU	A	K23 R26	K23 R26

Gene Ontology

Molecular Function

• GO:0016853 isomerase activity

External links

• PDB: RCSB:4q0q, PDBe:4q0q, PDBj:4q0q
• PDBsum: 4q0q
• PubMed: 24846739
• UniProt: Q93UQ5