Structure of PDB 4pwy Chain A

Receptor sequence
>4pwyA (length=250) Species: 9606 (Homo sapiens) [Search protein sequence]
GSVRRFESFNLFSVTEGAWVQYTSIFCPEYSISLRHSLNVEDVLTSFDNT
GNVCIWPSEEVLAYYCLKHNNIFRALAVCELGGGMTCLAGLMVAISADVK
EVLLTDGNEKAIRNVQDIITRNQKAGVFKTQKISSCFLRWDNETDVSQLE
GHFDIVMCADCLFLDQYRASLVDAIKRLLQPRGKAMVFAPRRGNTLNQFC
NLAEKAGFCIQRHENYDEHISNFHSKLKKENPDIYEENLHYPLLLILTKH
3D structure
PDB4pwy Crystal structure of a Calmodulin-lysine N-methyltransferase fragment
ChainA
Resolution1.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.1.1.60: calmodulin-lysine N-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A W128 E131 G154 G156 D178 G179 R211 W212 A231 Y239 W56 E59 G82 G84 D106 G107 R139 W140 A159 Y167
Gene Ontology
Molecular Function
GO:0018025 calmodulin-lysine N-methyltransferase activity
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4pwy, PDBe:4pwy, PDBj:4pwy
PDBsum4pwy
PubMed
UniProtQ7Z624|CMKMT_HUMAN Calmodulin-lysine N-methyltransferase (Gene Name=CAMKMT)

[Back to BioLiP]