Structure of PDB 4pwg Chain A

Receptor sequence
>4pwgA (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
CPLMVKVLDAVRGSPAINVAMHVFRKAADDTWEPFASGKTSESGELHGLT
TEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAA
LLSPYSYSTTAVVTNP
3D structure
PDB4pwg Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
ChainA
Resolution1.798 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0XR A K15 L17 S117 T119 K6 L8 S108 T110 BindingDB: EC50=23000nM
BS02 CA A C10 H56 C1 H47
External links
PDB RCSB:4pwg, PDBe:4pwg, PDBj:4pwg
PDBsum4pwg
PubMed25314129
UniProtP02766|TTHY_HUMAN Transthyretin (Gene Name=TTR)

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