Structure of PDB 4pth Chain A

Receptor sequence

>4pthA (length=159) Species: 316385 (Escherichia coli str. K-12 substr. DH10B)

MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESI
GRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVY
EQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHS
YCFEILERR

3D structure

• PDB: 4pth Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR.
• Chain: A
• Resolution: 0.85 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NAP	A	A6 A7 I14 N18 A19 M20 G43 R44 H45 T46 L62 S63 S64 Q65 K76 I94 G96 G97 R98 V99 Q102 T123	A6 A7 I14 N18 A19 M20 G43 R44 H45 T46 L62 S63 S64 Q65 K76 I94 G96 G97 R98 V99 Q102 T123
BS02	MN	A	D116 A117 H149	D116 A117 H149

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Thu Nov 28 17:07:54 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1443                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)

   1444         else:

=> 1445             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)

   1446     

   1447     uniprot_line=''

pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '4pth', asym_id = 'A', title = 'Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR.'

 /var/www/html/BioLiP/pdb.cgi in display_protein_receptor(pdbid='4pth', asym_id='A', title='Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR.')

    839 

    840     if go:

=>  841         display_go(go,uniprot,pdbid,asym_id)

    842     return pubmed,uniprot

    843 

global display_go = <function display_go>, go = '0004146,0046654,0050661', uniprot = '', pdbid = '4pth', asym_id = 'A'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0004146,0046654,0050661', uniprot='', pdbid='4pth', asym_id='A')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>