Structure of PDB 4pqg Chain A

Receptor sequence
>4pqgA (length=506) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence]
HHHMTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMILADN
IQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREK
NGKVLRVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRY
CSEYFAPKDNVAVLYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGK
QAFVRAFMKSLNLNKSDLVILDRETGIGQVVFEEAQTAHLAVVVHAEHYS
ENATNEDYILWNNYYDYQFTNADKVDFFIVSTDRQNEVLQEQFAKYTQHQ
PKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKHIDWLVKAVIEAHK
ELPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYSQYEVY
LTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSD
HVEDQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTV
EEVLHD
3D structure
PDB4pqg Structure of a Novel O-Linked N-Acetyl-d-glucosamine (O-GlcNAc) Transferase, GtfA, Reveals Insights into the Glycosylation of Pneumococcal Serine-rich Repeat Adhesins.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UDP A G16 Y19 R328 K333 Y357 G358 H384 A385 L387 G407 L408 T409 E412 G19 Y22 R331 K336 Y360 G361 H387 A388 L390 G410 L411 T412 E415
BS02 NAG A G16 H242 A243 V305 E404 G405 F406 G407 G19 H245 A246 V308 E407 G408 F409 G410
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016757 glycosyltransferase activity
Biological Process
GO:0006486 protein glycosylation
GO:0018242 protein O-linked glycosylation via serine
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0017122 protein N-acetylglucosaminyltransferase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4pqg, PDBe:4pqg, PDBj:4pqg
PDBsum4pqg
PubMed24936067
UniProtA0A0H2URG7|GTFA_STRPN UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase GtfA subunit (Gene Name=gtfA)

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