Structure of PDB 4ppr Chain A

Receptor sequence
>4pprA (length=300) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
PLPLVVPPTPVGGNALGGCGIITAPGSAPAPGDVSAEAWLVADLDSGAVI
AARDPHGRHRPASVIKVLVAMASINTLTLNKSVAGTADDAAVEGTKVGVN
TGGTYTVNQLLHGLLMHSGNDAAYALARQLGGMPAALEKINLLAAKLGGR
DTRVATPSGLDGPGMSTSAYDIGLFYRYAWQNPVFADIVATRTFDFPGHG
DHPGYELENDNQLLYNYPGALGGKTGYTDDAGQTFVGAANRDGRRLMTVL
LHGTRQPIPPWEQAAHLLDYGFNTPAGTQIGTLIEPDPSLMSTDRRVDPQ
3D structure
PDB4ppr Subfamily-specific adaptations in the structures of two penicillin-binding proteins from Mycobacterium tuberculosis.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.16.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MER A S121 T153 S176 N178 L218 T283 G284 Y285 Q291 S63 T95 S118 N120 L160 T225 G226 Y227 Q233
Gene Ontology
Molecular Function
GO:0009002 serine-type D-Ala-D-Ala carboxypeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:4ppr, PDBe:4ppr, PDBj:4ppr
PDBsum4ppr
PubMed25551456
UniProtO53380|DACB1_MYCTU D-alanyl-D-alanine carboxypeptidase DacB1 (Gene Name=dacB1)

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