Structure of PDB 4ppp Chain A

Receptor sequence
>4pppA (length=228) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEFSEASMMGLLTNLADRELVHMINW
AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLL
DRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYT
FKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNK
GMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB4ppp Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network.
ChainA
Resolution2.686 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I358 K362 V376 E542 I48 K52 V66 E222
BS02 FSV A M343 E353 L387 M388 M421 H524 M33 E43 L77 M78 M111 H204
External links
PDB RCSB:4ppp, PDBe:4ppp, PDBj:4ppp
PDBsum4ppp
PubMed24771768
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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