Structure of PDB 4pnf Chain A

Receptor sequence
>4pnfA (length=220) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
VKLTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNP
QHTVPTLEDDGHYIWDSHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLH
FESGVVFANGIRSISKSVLFQGQTKVPKERYDAIIEIYDFVETFLKGQDY
IAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIKKLEQLPYYEEA
NGKGVRQLVAIFKKTNFTFE
3D structure
PDB4pnf Comparison of epsilon- and delta-class glutathione S-transferases: the crystal structures of the glutathione S-transferases DmGSTE6 and DmGSTE7 from Drosophila melanogaster.
ChainA
Resolution2.11 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S12
Catalytic site (residue number reindexed from 1) S11
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH A S12 P14 Q41 H53 T54 V55 D67 S68 H69 F108 R113 S11 P13 Q40 H52 T53 V54 D66 S67 H68 F107 R112
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004364 glutathione transferase activity
Biological Process
GO:0006749 glutathione metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4pnf, PDBe:4pnf, PDBj:4pnf
PDBsum4pnf
PubMed26457432
UniProtQ7JZM3

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