Structure of PDB 4pn1 Chain A

Receptor sequence
>4pn1A (length=259) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence]
KIEMNFLNKPIVPDTTKVISNFLTHYLITEPVEHVEIEAKLGTLIDLETQ
NRFEFPVMNETILNPEFNLRTRFESDMTASEHKYLNEFLNQAFRDSQKPG
RLPFAYKHTKQVDLFYETEDNDKIRVSKNQSDNQVLACVKKRRVADLFLY
CPNDAFDIRISISDELPVSMPSGNQQPSLTRLKDRVGYVHQEIKIDLTKT
TQNDPVYDTTERHELEVEFGNIADLRDRAQKAKDGMEAPLFRRVQLFMDN
VRILRREHS
3D structure
PDB4pn1 Fission yeast RNA triphosphatase reads an Spt5 CTD code.
ChainA
Resolution2.803 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) E78 E80 R169 K185 K227 E262
Catalytic site (residue number reindexed from 1) E36 E38 R125 K141 K183 E218
Enzyme Commision number 3.6.1.74: mRNA 5'-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V60 N63 F64 H67 N106 E108 V18 N21 F22 H25 N64 E66
Gene Ontology
Molecular Function
GO:0004651 polynucleotide 5'-phosphatase activity
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0099122 RNA polymerase II C-terminal domain binding
GO:0140818 mRNA 5'-triphosphate monophosphatase activity
Biological Process
GO:0006370 7-methylguanosine mRNA capping
Cellular Component
GO:0005634 nucleus
GO:0031533 mRNA capping enzyme complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4pn1, PDBe:4pn1, PDBj:4pn1
PDBsum4pn1
PubMed25414009
UniProtQ9P6Q6|CET1_SCHPO mRNA-capping enzyme subunit beta (Gene Name=pct1)

[Back to BioLiP]