Structure of PDB 4pln Chain A

Receptor sequence
>4plnA (length=417) Species: 9031 (Gallus gallus) [Search protein sequence]
PDPCYDEHGLPRRCIPDFVNSAFGKEVKVSSTCGKPPSRYCVVTEKGEEQ
VRSCHLCNASDPKRAHPPSFLTDLNNPHNLTCWQSDSYVQYPHNVTLTLS
LGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKTWVPFQFYSTQCRKMYNK
PSRAAITKQNEQEAICTDSHTDVRPLSGGLIAFSTLDGRPTAHDFDNSPV
LQDWVTATDIKVTFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKC
NGHASRCVRDRDDNLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREANE
CVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGF
YRDLSKPISHRKACKECDCHPVGAAGQTCNQTTGQCPCKDGVTGITCNRC
AKGYQQSRSPIAPCIKI
3D structure
PDB4pln Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism.
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A F109 D112 T120 S279 F70 D73 T81 S240
External links
PDB RCSB:4pln, PDBe:4pln, PDBj:4pln
PDBsum4pln
PubMed24876346
UniProtQ90922|NET1_CHICK Netrin-1 (Gene Name=NTN1)

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