Structure of PDB 4pl7 Chain A |
>4pl7A (length=382) Species: 9606,644223 [Search protein sequence] |
VAALVIDNGSGMCKAGYAGDDAPHTVFPSVVGSFVGDEAQSKRGILTLRY PIEHGIVTNWDDMEKIWHHTFYNELRLAPEEHPVLLTEAPMNPKSNREKM TQIMFETFNVPAFYVSIQAVLSLYASGRTTGIVLDSGDGVTHVVPIYAGF SLPHAILRIDLAGRDLTDYLMKILSERGYTFSTSAEREIVRDIKEKLCYV ALDFDQELQTSSQSSSIEKSYELPDGQVITIGNERFRAPEALFHPSVLGL EASGIDQTTYNSIMKCDVDVRKELYSNIVMSGGTTMFPGIAERMQKELTA LAPSSMKVKISAPPERKYSVWIGGSILASLGTFQQMWISKQEYDESDMAE IEKFDKSKLKKTETQEKNPLPSKETIEQEKQA |
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PDB | 4pl7 Structural basis of thymosin-beta 4/profilin exchange leading to actin filament polymerization. |
Chain | A |
Resolution | 2.3 Å |
3D structure |
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Biological Process |
GO:0007015 |
actin filament organization |
GO:0030334 |
regulation of cell migration |
GO:0033209 |
tumor necrosis factor-mediated signaling pathway |
GO:0042989 |
sequestering of actin monomers |
GO:0043124 |
negative regulation of canonical NF-kappaB signal transduction |
GO:0043536 |
positive regulation of blood vessel endothelial cell migration |
GO:0050728 |
negative regulation of inflammatory response |
GO:1905273 |
positive regulation of proton-transporting ATP synthase activity, rotational mechanism |
GO:2001028 |
positive regulation of endothelial cell chemotaxis |
GO:2001171 |
positive regulation of ATP biosynthetic process |
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