Structure of PDB 4phn Chain A

Receptor sequence
>4phnA (length=173) Species: 9823 (Sus scrofa) [Search protein sequence]
EEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCR
SMVAVMDSDTTGKLGFEEFKYLWNNIKKWQAIYKQFDVDRSGTIGSSELP
GAFEAAGFHLNEHLYSMIIRRYSDEGGNMDFDNFISCLVRLDAMFRAFKS
LDKDGTGQIQVNIQEWLQLTMYS
3D structure
PDB4phn The structural basis of differential inhibition of human calpain by indole and phenyl alpha-mercaptoacrylic acids.
ChainA
Resolution1.79 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F162 G185 I187
Catalytic site (residue number reindexed from 1) F69 G92 I94
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A A107 D110 E112 E117 A14 D17 E19 E24
BS02 CA A D150 D152 T154 K156 E161 D57 D59 T61 K63 E68
BS03 CA A D180 D182 S184 T186 E191 D87 D89 S91 T93 E98
BS04 CA A D135 D223 D225 N226 D42 D130 D132 N133
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:4phn, PDBe:4phn, PDBj:4phn
PDBsum4phn
PubMed25086406
UniProtP04574|CPNS1_PIG Calpain small subunit 1 (Gene Name=CAPNS1)

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