Structure of PDB 4pfo Chain A

Receptor sequence
>4pfoA (length=755) Species: 9823 (Sus scrofa) [Search protein sequence]
KPVWAPHPTDGFQVGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEED
SKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIP
KIYSSETIKSYQGKSLGTMPPHVFAIADKAFRDMKVLKLSQSIIVSGESG
AGKTENTKFVLRYLTESYGTDRIVEANPLLEAFGNAKTVRNNNSSRFGKF
VEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAGASEDI
RERLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPEYLKAGSLKDP
LLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGSTS
GGCNLKNKSTQALEYCAELLGLDQDDLRVSLTTRVMVIKVPLKVEQANNA
RDALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFE
QFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIE
ARLVGILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLSIPRKSKLAIHR
NIRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRE
LFELSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQ
ILSQLQCSGMVSVLDLMQGGFPSRASFHELYNMYKKYMPDKLARLDPRLF
CKALFKALGLNEIDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRV
NHWLI
3D structure
PDB4pfo How actin initiates the motor activity of Myosin.
ChainA
Resolution1.75 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S153 G154 T158 N200 S203 S204 G459 E461
Catalytic site (residue number reindexed from 1) S149 G150 T154 N191 S194 S195 G440 E442
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A T158 S204 T154 S195
BS02 ADP A N98 P99 G154 G156 K157 T158 E159 N200 N94 P95 G150 G152 K153 T154 E155 N191
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:4pfo, PDBe:4pfo, PDBj:4pfo
PDBsum4pfo
PubMed25936506
UniProtF1RQI7

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