Structure of PDB 4pf4 Chain A

Receptor sequence
>4pf4A (length=278) Species: 9606 (Homo sapiens) [Search protein sequence]
HMTVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRT
KSSRRGVSREDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGG
ELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLD
RNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEAD
MWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAK
DFIRRLLVKDPKKRMTIQDSLQHPWIKP
3D structure
PDB4pf4 1.1A X-RAY STRUCTURE OF THE APO CATALYTIC DOMAIN OF DEATH-ASSOCIATED PROTEIN KINASE 1, aa 1-277
ChainA
Resolution1.13 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D139 K141 E143 N144 D161 T180
Catalytic site (residue number reindexed from 1) D140 K142 E144 N145 D162 T181
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A K42 D161 K43 D162
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:4pf4, PDBe:4pf4, PDBj:4pf4
PDBsum4pf4
PubMed
UniProtP53355|DAPK1_HUMAN Death-associated protein kinase 1 (Gene Name=DAPK1)

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