Structure of PDB 4pdw Chain A

Receptor sequence
>4pdwA (length=274) Species: 12131 (rhinovirus B14) [Search protein sequence]
QTVASISSGPKHTQKVPILTANETGATMPVLPSDSIETRTTYMHFNGSET
DVECFLGRAACVHVTEIQNKDATGIDNHREAKLFNDWKINLSSLVQLRKK
LELFTYVRFDSEYTILATASQPDSANYSSNLVVQAMYVPPGAPNPKEWDD
YTWQSASNPSVFFKVGDTSRFSVPYVGLASAYNCFYDGYSHDDAETQYGI
TVLNHMGSMAFRIVNEHDEHKTLVKIRVYHRAKHVEAWIPRAPRALPYTS
IGRTNYPKNTEPVIKKRKGDIKSY
3D structure
PDB4pdw A novel benzonitrile analogue inhibits rhinovirus replication.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2XK A Y128 Y152 F186 Y197 M221 M224 Y113 Y137 F171 Y182 M206 M209
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:4pdw, PDBe:4pdw, PDBj:4pdw
PDBsum4pdw
PubMed24948704
UniProtP03303|POLG_HRV14 Genome polyprotein

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