Structure of PDB 4pd6 Chain A

Receptor sequence
>4pd6A (length=401) Species: 243277 (Vibrio cholerae O1 biovar El Tor str. N16961) [Search protein sequence]
MSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQE
LLRGFSDAVSNVINYGNDGTSFLFGGLVSGKMFEVFGGGGFIFAFRVLPT
LIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQ
TEAPLVVRPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVA
ASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGGASAGLQLALNVGA
MLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWN
EATVAGEFIGLKTVANEFVAYSQFAPYLTEAAPVVLSEKTKAIISFALCG
FANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIAGFF
L
3D structure
PDB4pd6 Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters.
ChainA
Resolution2.08 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 URI A Q154 E332 F366 S371 I374 Q150 E317 F351 S356 I359 MOAD: Kd=36uM
PDBbind-CN: -logKd/Ki=4.44,Kd=36uM
Gene Ontology
Molecular Function
GO:0005337 nucleoside transmembrane transporter activity
GO:0015293 symporter activity
GO:0042802 identical protein binding
Biological Process
GO:1901642 nucleoside transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4pd6, PDBe:4pd6, PDBj:4pd6
PDBsum4pd6
PubMed25082345
UniProtQ9KPL5

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