Structure of PDB 4pc8 Chain A

Receptor sequence
>4pc8A (length=239) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
MSKPQPIAAANWKSGSPDSLSELIDLFNSTSINHDVQCVVASTFVHLAMT
KERLSHPKFVIAALNAGNADALASLKDFGVNWIVLGHSERRWYYGETNEI
VADKVAAAVASGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKAD
WAKVVIAYEPVWAIGTGKVATPQQAQEAHALIRSWVSSKIGADVAGELRI
LYGGSVNGKNARTLYQQRDVNGFLAGLKPEFVDIIKATQ
3D structure
PDB4pc8 Crystal structures of two monomeric triosephosphate isomerase variants identified via a directed-evolution protocol selecting for L-arabinose isomerase activity.
ChainA
Resolution1.55 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N11 K13 H95 E97 E167 G173 S213
Catalytic site (residue number reindexed from 1) N11 K13 H87 E89 E159 G165 S205
Enzyme Commision number 5.3.1.1: triose-phosphate isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GOA A G173 S213 G165 S205
Gene Ontology
Molecular Function
GO:0004807 triose-phosphate isomerase activity
Biological Process
GO:0006096 glycolytic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4pc8, PDBe:4pc8, PDBj:4pc8
PDBsum4pc8
PubMed27303904
UniProtP04789|TPIS_TRYBB Triosephosphate isomerase, glycosomal

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