Structure of PDB 4pc2 Chain A

Receptor sequence
>4pc2A (length=363) Species: 316385 (Escherichia coli str. K-12 substr. DH10B) [Search protein sequence]
TKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGSHVEYDTPTRHYAHVD
CPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYI
IVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEG
DAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGR
VERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRG
IKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQF
YFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGG
RTVGAGVVAKVLG
3D structure
PDB4pc2 Structural outline of the detailed mechanism for elongation factor Ts-mediated guanine nucleotide exchange on elongation factor Tu.
ChainA
Resolution2.1999 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D21 K24 T25 H84
Catalytic site (residue number reindexed from 1) D14 K17 T18 H54
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A D21 G23 K24 T25 T26 N135 K136 D138 S173 A174 L175 D14 G16 K17 T18 T19 N105 K106 D108 S143 A144 L145
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0097216 guanosine tetraphosphate binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:4pc2, PDBe:4pc2, PDBj:4pc2
PDBsum4pc2
PubMed26073967
UniProtA0A0M3KKV1

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