Structure of PDB 4pb2 Chain A

Receptor sequence
>4pb2A (length=404) Species: 243277 (Vibrio cholerae O1 biovar El Tor str. N16961) [Search protein sequence]
SLFMSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPW
GQELLRGFSDAVSNVINYGNDGTSFLFGGLVSGKMFEVFGGGGFIFAFRV
LPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIF
VGQTEAPLVVRPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEY
LVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGGASAGLQLALN
VGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGV
PWNEATVAGEFIGLKTVANEFVAYSQFAPYLTEAAPVVLSEKTKAIISFA
LCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIA
GFFL
3D structure
PDB4pb2 Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters.
ChainA
Resolution2.302 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5UD A Q154 E332 F366 S371 Q153 E320 F354 S359 MOAD: Kd=16uM
PDBbind-CN: -logKd/Ki=4.80,Kd=16uM
Gene Ontology
Molecular Function
GO:0005337 nucleoside transmembrane transporter activity
GO:0015293 symporter activity
GO:0042802 identical protein binding
Biological Process
GO:1901642 nucleoside transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4pb2, PDBe:4pb2, PDBj:4pb2
PDBsum4pb2
PubMed25082345
UniProtQ9KPL5

[Back to BioLiP]