Structure of PDB 4pb1 Chain A

Receptor sequence
>4pb1A (length=404) Species: 243277 (Vibrio cholerae O1 biovar El Tor str. N16961) [Search protein sequence]
SLFMSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPW
GQELLRGFSDAVSNVINYGNDGTSFLFGGLVSGKMFEVFGGGGFIFAFRV
LPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIF
VGQTEAPLVVRPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEY
LVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGGASAGLQLALN
VGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGV
PWNEATVAGEFIGLKTVANEFVAYSQFAPYLTEAAPVVLSEKTKAIISFA
LCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIA
GFFL
3D structure
PDB4pb1 Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters.
ChainA
Resolution2.803 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RBV A L259 N331 E332 F333 F366 L247 N319 E320 F321 F354 PDBbind-CN: -logKd/Ki=2.82,Kd=1530uM
Gene Ontology
Molecular Function
GO:0005337 nucleoside transmembrane transporter activity
GO:0015293 symporter activity
GO:0042802 identical protein binding
Biological Process
GO:1901642 nucleoside transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4pb1, PDBe:4pb1, PDBj:4pb1
PDBsum4pb1
PubMed25082345
UniProtQ9KPL5

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