Structure of PDB 4p9c Chain A

Receptor sequence
>4p9cA (length=136) Species: 1137745 (Cyanophage S-TIM5) [Search protein sequence]
HMKPEIKEAYMKTAELFSQVSNCKRMKVGAIVVKNGSILAHGWNGTPSGF
HTNCCELEDGSTNPFVLHAEQNALVKMAKSSESIDGSELFCTHSPCPDCS
KMIAQAGVKKVYYRNEYRITDGIDVLQQLGVEVEKM
3D structure
PDB4p9c The First Crystal Structure of a dTTP-bound Deoxycytidylate Deaminase Validates and Details the Allosteric-Inhibitor Binding Site.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A H67 C95 C98 H68 C96 C99
BS02 DCM A H40 W42 G44 T45 S47 N71 K75 H41 W43 G45 T46 S48 N72 K76
BS03 DU A R24 V27 N43 T61 H67 E69 C95 Y116 R117 R25 V28 N44 T62 H68 E70 C96 Y117 R118
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0004132 dCMP deaminase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006220 pyrimidine nucleotide metabolic process

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Molecular Function

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Biological Process
External links
PDB RCSB:4p9c, PDBe:4p9c, PDBj:4p9c
PDBsum4p9c
PubMed25404739
UniProtH6WFU3

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