Structure of PDB 4p7i Chain A

Receptor sequence
>4p7iA (length=294) Species: 10090 (Mus musculus) [Search protein sequence]
PKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTI
KDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLF
FLQVKKQILDEKVYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEEL
LPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYG
VNYFTIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSD
KEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRK
3D structure
PDB4p7i Structural basis of the binding of Merlin FERM domain to the E3 ubiquitin ligase substrate adaptor DCAF1.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I261 R262 N263 I264 S265 Y266 I301 H304 M308 R309 K312 I243 R244 N245 I246 S247 Y248 I283 H286 M290 R291 K294
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0008092 cytoskeletal protein binding
Cellular Component
GO:0005856 cytoskeleton

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Molecular Function
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Cellular Component
External links
PDB RCSB:4p7i, PDBe:4p7i, PDBj:4p7i
PDBsum4p7i
PubMed24706749
UniProtP46662|MERL_MOUSE Merlin (Gene Name=Nf2)

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