Structure of PDB 4p4l Chain A

Receptor sequence
>4p4lA (length=264) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
PKKAGVLGSPIAHSRSPQLHLAAYRALGLHDWTYERIECGAAELPVVVGG
FGPEWVGVSVTMPGKFAALRFADERTARADLVGSANTLVRTPHGWRADNT
DIDGVAGALGAAAGHALVLGSGGTAPAAVVGLAELGVTDITVVARNSDKA
ARLVDLGTRVGVATRFCAFDSGGLADAVAAAEVLVSTIPAEVAAGYAGTL
AAIPVLLDAIYDPWPTPLAAAVGSAGGRVISGLQMLLHQAFAQVEQFTGL
PAPREAMTCALAAL
3D structure
PDB4p4l Structure of Mycobacterium tuberculosis Shikimate Dehydrogenase
ChainA
Resolution2.009 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.25: shikimate dehydrogenase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SKM A S18 S20 T65 K69 N90 D105 L240 Q243 S14 S16 T61 K65 N86 D101 L236 Q239
Gene Ontology
Molecular Function
GO:0004764 shikimate 3-dehydrogenase (NADP+) activity
GO:0050661 NADP binding
Biological Process
GO:0009423 chorismate biosynthetic process
GO:0019632 shikimate metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4p4l, PDBe:4p4l, PDBj:4p4l
PDBsum4p4l
PubMed
UniProtI6Y120

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