Structure of PDB 4p42 Chain A

Receptor sequence
>4p42A (length=455) Species: 9606 (Homo sapiens) [Search protein sequence]
DTERAEWLNKTVKHMWPFICQFIEKLFRETIEPAVRGANTHLSTFSFTKV
DVGQQPLRINGVKVYTENVDKRQIILDLQISFVGNCEIDLEIKRYFCRAG
VKSIQIHGTMRVILEPLIGDMPLVGALSIFFLRKPLLEINWTGLTNLLDV
PGLNGLSDTIILDIISNYLVLPNRITVPLVSEVQIAQLRFPVPKGVLRIH
FIEAQDLQGKDTYLKGLVKGKSDPYGIIRVGNQIFQSRVIKENLSPKWNE
VYEALVYEHPGQELEIELFDEDPDKDDFLGSLMIDLIEVEKERLLDEWFT
LDEVPKGKLHLRLEWLTLMPNASNLDKVLTDIGLSSALLILYLDSARNLP
SSSNPNPVVQMSVGHKAQESKIRYKTNEPVWEENFTFFIHNPKRQDLEVE
VRDEQHQCSLGNLKVPLSQLLTSEDMTVSQRFQLSNSGPNSTIKMKIALR
VLHLE
3D structure
PDB4p42 Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer.
ChainA
Resolution2.44 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EGC A M272 L331 P334 N335 R336 I337 M110 L169 P172 N173 R174 I175
Gene Ontology
Biological Process
GO:0006869 lipid transport
GO:0061817 endoplasmic reticulum-plasma membrane tethering

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Molecular Function
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Biological Process
External links
PDB RCSB:4p42, PDBe:4p42, PDBj:4p42
PDBsum4p42
PubMed24847877
UniProtA0FGR8|ESYT2_HUMAN Extended synaptotagmin-2 (Gene Name=ESYT2)

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