Structure of PDB 4p2o Chain A

Receptor sequence
>4p2oA (length=175) Species: 10090 (Mus musculus) [Search protein sequence]
IKEEHTIIQAEFYLLPDKRGEFMFDFDGDEIFHVDIEKSETIWRLEEFAK
FASFEAQGALANIAVDKANLDVMKERSANVAPEVTVLSRSPVNLGEPNIL
ICFIDKFSPPVVNVTWLRNGRPVTEGVSETVFLPRDDHLFRKFHYLTFLP
STDDFYDCEVDHWGLEEPLRKHWEF
3D structure
PDB4p2o Deconstructing the Peptide-MHC Specificity of T Cell Recognition.
ChainA
Resolution2.603 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Q9 F51 A52 S53 F54 G58 N62 V65 N69 V72 R76 Q9 F51 A52 S53 F54 G58 N62 V65 N69 V72 R76
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4p2o, PDBe:4p2o, PDBj:4p2o
PDBsum4p2o
PubMed24855945
UniProtP04224|HA22_MOUSE H-2 class II histocompatibility antigen, E-K alpha chain

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