Structure of PDB 4p2l Chain A

Receptor sequence
>4p2lA (length=498) Species: 10116 (Rattus norvegicus) [Search protein sequence]
VLYSSSDPLTLLDADTVRPAVLGSSSAWAVEFFASWCGHCIAFAPTWKEL
ANDVKDWRPALNLAVLDCADETNSAVCREFNIAGFPTVRFFKAFSKNGTG
TALPAAGANVQTLRMRLIDALESHRDTWPPACPPLEPAKLKDINEFFTRS
KAEYLALIFEREDSYLGREVTLDLSQFHAVAVRRVLNSESDVVSKFAVTD
FPSCYLLLRNGSVSRVPVLVESRPFYTSYLRGLPGLTREAPPPTVWKFAD
RSKIYMADLESALHYILRVEVGKFSVLEGQRLVALKKFVAVLAKYFPGQP
LVQNFLHSINDWLQKQQKKKIPYSYFKAALDSHKENAVLAEKVNWIGCQG
SEPHFRGFPCSLWVLFHFLTVQAHRYSEAHPQEPADGQEVLQAMRSYVQS
FFGCRDCANHFEQMAAASMHQVKSPSNAVLWLWTSHNRVNARLSGALSED
PQFPKVQWPPRELCSACHNEVNGVPLWDLGATLNFLKAHFSPANIVRD
3D structure
PDB4p2l Enzyme structure captures four cysteines aligned for disulfide relay.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.8.3.2: thiol oxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A R404 P407 C408 W411 H415 C455 F459 W481 H484 N485 N488 R490 L491 K503 W506 R356 P359 C360 W363 H367 C407 F411 W433 H436 N437 N440 R442 L443 K455 W458
Gene Ontology
Molecular Function
GO:0016971 flavin-dependent sulfhydryl oxidase activity
GO:0016972 thiol oxidase activity

View graph for
Molecular Function
External links
PDB RCSB:4p2l, PDBe:4p2l, PDBj:4p2l
PDBsum4p2l
PubMed24888638
UniProtQ6IUU3|QSOX1_RAT Sulfhydryl oxidase 1 (Gene Name=Qsox1)

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