Structure of PDB 4p0g Chain A

Receptor sequence
>4p0gA (length=429) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
APTALERVQKEGVLRVITRNSPATYFQDRNGETGFEYELAKRFAERLGVE
LKIETADNLDDLYAQLSREGGPALAAAGLTPGREDDASVRYSHTYLDVTP
QIIYRNGQQRPTRPEDLVGKRIMVLKGSSHAEQLAELKKQYPELKYEESD
AVEVVDLLRMVDVGDIDLTLVDSNELAMNQVYFPNVRVAFDFGEARGLAW
ALPGGDDDSLMNEVNAFLDQAKKEGLLQRLKDRYYGHVDVLGYVGAYTFA
QHLQQRLPRYESHFKQSGKQLDTDWRLLAAIGYQESLWQPGATSKTGVRG
LMMLTNRTAQAMGVSNRLDPKQSIQGGSKYFVQIRSELPESIKEPDRSWF
ALAAYNIGGAHLEDARKMAEKEGLNPNKWLDVKKMLPRLAQKQWYAKTRY
GYARGGETVHFVQNVRRYYDILTWVTQPQ
3D structure
PDB4p0g Crystal structure of MltF from Pseudomonas aeruginosa complexed with bulgecin and muropeptide
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.2.n1: peptidoglycan lytic exotransglycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BLG A E316 K326 T327 M334 L335 T336 T339 Y361 Y386 N387 I388 G389 R435 E438 E285 K295 T296 M303 L304 T305 T308 Y330 Y355 N356 I357 G358 R404 E407
Gene Ontology
Molecular Function
GO:0008933 lytic transglycosylase activity
GO:0016837 carbon-oxygen lyase activity, acting on polysaccharides
Biological Process
GO:0000270 peptidoglycan metabolic process
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4p0g, PDBe:4p0g, PDBj:4p0g
PDBsum4p0g
PubMed
UniProtQ9HXN1|MLTF_PSEAE Membrane-bound lytic murein transglycosylase F (Gene Name=mltF)

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