Structure of PDB 4ozv Chain A

Receptor sequence
>4ozvA (length=333) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
ADLVPPPGYYAAVGERKAGSCPAVPPPYTGSLVFTSKYEGSDSARATLNV
KAEKTFRSQIKDITDMERGATKLVTQYMRSGRDGDLACALNWMSAWARAG
ALQSDDFNHTGKSMRKWALGSLSGAYMRLKFSSSRPLAAHAEQSREIEDW
FARLGTQVVRDWSGLPLKKINNHSYWAAWSVMSTAVVTNRRDLFDWAVSE
FKVAANQVDEQGFLPNELKRRQRALAYHNYALPPLAMIAAFAQVNGVDLR
QENHGALQRLAERVMKGVDDEETFEEKTGEDQDMTDLKVDNKYAWLEPYC
ALYRCEPKMLEAKKDREPFNSFRLGGEVTRVFS
3D structure
PDB4ozv The Pseudomonas aeruginosa homeostasis enzyme AlgL clears the periplasmic space of accumulated alginate during polymer biosynthesis.
ChainA
Resolution1.642 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y67 N201 H202 R249 Y256
Catalytic site (residue number reindexed from 1) Y38 N172 H173 R220 Y227
Enzyme Commision number 4.2.2.3: mannuronate-specific alginate lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BEM A K66 Y67 R74 H202 Y256 K37 Y38 R45 H173 Y227
Gene Ontology
Molecular Function
GO:0004794 threonine deaminase activity
GO:0016829 lyase activity
GO:0045135 poly(beta-D-mannuronate) lyase activity
Biological Process
GO:0042121 alginic acid biosynthetic process
GO:0042122 alginic acid catabolic process
Cellular Component
GO:0042597 periplasmic space

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Cellular Component
External links
PDB RCSB:4ozv, PDBe:4ozv, PDBj:4ozv
PDBsum4ozv
PubMed34990713
UniProtQ06749|ALGL_PSEAE Alginate lyase (Gene Name=algL)

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