Structure of PDB 4owd Chain A

Receptor sequence
>4owdA (length=428) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
PTALERVQKEGVLRVITRNSPATYFQDRNGETGFEYELAKRFAERLGVEL
KIETADNLDDLYAQLSREGGPALAAAGLTPGREDDASVRYSHTYLDVTPQ
IIYRNGQQRPTRPEDLVGKRIMVLKGSSHAEQLAELKKQYPELKYEESDA
VEVVDLLRMVDVGDIDLTLVDSNELAMNQVYFPNVRVAFDFGEARGLAWA
LPGGDDDSLMNEVNAFLDQAKKEGLLQRLKDRYYGHVDVLGYVGAYTFAQ
HLQQRLPRYESHFKQSGKQLDTDWRLLAAIGYQESLWQPGATSKTGVRGL
MMLTNRTAQAMGVSNRLDPKQSIQGGSKYFVQIRSELPESIKEPDRSWFA
LAAYNIGGAHLEDARKMAEKEGLNPNKWLDVKKMLPRLAQKQWYAKTRYG
YARGGETVHFVQNVRRYYDILTWVTQPQ
3D structure
PDB4owd Crystal structure of MltF from Pseudomonas aeruginosa complexed with cysteine
ChainA
Resolution2.21 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.2.n1: peptidoglycan lytic exotransglycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CYS A G109 L110 T111 S159 S160 H161 D203 G77 L78 T79 S127 S128 H129 D171
Gene Ontology
Molecular Function
GO:0008933 lytic transglycosylase activity
GO:0016829 lyase activity
GO:0016837 carbon-oxygen lyase activity, acting on polysaccharides
Biological Process
GO:0000270 peptidoglycan metabolic process
GO:0009253 peptidoglycan catabolic process
GO:0016998 cell wall macromolecule catabolic process
GO:0071555 cell wall organization
Cellular Component
GO:0009279 cell outer membrane
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:4owd, PDBe:4owd, PDBj:4owd
PDBsum4owd
PubMed
UniProtQ9HXN1|MLTF_PSEAE Membrane-bound lytic murein transglycosylase F (Gene Name=mltF)

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