Structure of PDB 4oue Chain A

Receptor sequence
>4oueA (length=459) Species: 226186 (Bacteroides thetaiotaomicron VPI-5482) [Search protein sequence]
SLAPCGLVPSARQLEWYNREMIAFFHFGINTFEEYVNEGDGKASTAIFNP
TALDCRQWMQTLKAAGIPAAILTAKHADGFCLWPSKYTDYSVKNAAWKNG
KGDVVREFVDACEEYGLKAGIYLGPHDRHEHLSPLYTTERYKEYYAHQLG
ELMSDYGKIWETWWDGAGADELTTPVYRHWYKIVREKQPDCVIFGTKNSY
PFADVRWMGNEAGEAGDPCWATTDSVAIRDEAQYYKGLNEGMLDGDAYIP
AETDVSIRPSWFYHAEEDSRVKSVRELWDIYCTSVGRNSVLLLNFPPDRR
GLIHSTDSLHAALLKQGIDETFSTNLLRGAKVKATNVRGAKYSPEKMLDN
EKNTYFAGKDGEVKADIIFTLPKTIEFDCLMIEEVIELGHRTTKWSVEYT
VDGKNWITIPEATDKQAIGHKWIVRLAPVKAKQVRLRIQDGKACPAIHTF
GVYKQSPVF
3D structure
PDB4oue Unraveling the Substrate Recognition Mechanism and Specificity of the Unusual Glycosyl Hydrolase Family 29 BT2192 from Bacteroides thetaiotaomicron.
ChainA
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.111: 1,3-alpha-L-fucosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IPT A D188 G189 A190 T219 W230 E234 E254 D277 D165 G166 A167 T196 W207 E211 E231 D254 PDBbind-CN: -logKd/Ki=3.30,Ki>500uM
Gene Ontology
Molecular Function
GO:0004560 alpha-L-fucosidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006004 fucose metabolic process
GO:0016139 glycoside catabolic process
Cellular Component
GO:0005764 lysosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4oue, PDBe:4oue, PDBj:4oue
PDBsum4oue
PubMed24527659
UniProtQ8A5P6

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