Structure of PDB 4or2 Chain A

Receptor sequence
>4or2A (length=360) Species: 562,9606 [Search protein sequence]
DLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDK
SPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAY
IQKYLIPVRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKS
SSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSAL
VTKTNRIARILARKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPI
LSYPSIKEVYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKTRNVPANFNE
AKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTCFAVSLSVTVALGCMFTP
KMYIIIAKPE
3D structure
PDB4or2 Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator
ChainA
Resolution2.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FM9 A R661 V664 V753 P756 L757 N760 I797 W798 F801 Y805 T815 A818 R186 V189 V270 P273 L274 N277 I314 W315 F318 Y322 T332 A335
BS02 CLR A W588 C601 F646 W113 C126 F171
BS03 CLR A I594 A598 L602 I119 A123 L127
BS04 CLR A W588 F646 W113 F171
BS05 CLR A T647 A650 T172 A175
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0022900 electron transport chain
Cellular Component
GO:0016020 membrane
GO:0042597 periplasmic space

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4or2, PDBe:4or2, PDBj:4or2
PDBsum4or2
PubMed24603153
UniProtP0ABE7|C562_ECOLX Soluble cytochrome b562 (Gene Name=cybC);
Q13255|GRM1_HUMAN Metabotropic glutamate receptor 1 (Gene Name=GRM1)

[Back to BioLiP]