Structure of PDB 4omj Chain A

Receptor sequence
>4omjA (length=274) Species: 9606 (Homo sapiens) [Search protein sequence]
MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQ
KSEAMLRKHVEFRKQKDIDNIISWQPPEVIQQYLSGGMCGYDLDGCPVWY
DIIGPLDAKGLLFSASKQDLLRTKMRECELLLQECAHQTTKLGRKVETIT
IIYDCEGLGLKHLWKPAVEAYGEFLCMFEENYPETLKRLFVVKAPKLFPV
AYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVEYGGTMTDPDG
NPKCKSKINYGGDIPRKYYVRDQV
3D structure
PDB4omj Structural insights on cholesterol endosynthesis: Binding of squalene and 2,3-oxidosqualene to supernatant protein factor.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 2TX A A108 Y153 H162 A167 A170 Y171 F174 L175 L189 A201 Y202 I205 A108 Y153 H162 A167 A170 Y171 F174 L175 L189 A201 Y202 I205 MOAD: Kd=5.44uM
PDBbind-CN: -logKd/Ki=5.26,Kd=5.44uM
External links
PDB RCSB:4omj, PDBe:4omj, PDBj:4omj
PDBsum4omj
PubMed25987292
UniProtO76054|S14L2_HUMAN SEC14-like protein 2 (Gene Name=SEC14L2)

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