Structure of PDB 4oke Chain A

Receptor sequence
>4okeA (length=160) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
VRYFYDTEFIEDGHTIELISIGVVAEDGREYYAVSTEFDPERAGSWVRTH
VLPKLPPPASQLWRSRQQIRLDLEEFLRIDGTDSIELWAWVGAYDHVALC
QLWGPMTALPPTVPRFTRELRQLWEDRGCPRMPPRPRDVHDALVDARDQL
RRFRLITSTD
3D structure
PDB4oke Structure and Function of RNase AS, a Polyadenylate-Specific Exoribonuclease Affecting Mycobacterial Virulence In Vivo
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.13.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A D6 E8 F9 W46 V47 H140 D6 E8 F9 W46 V47 H140
BS02 AMP A M106 R115 M106 R115
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
GO:0004532 RNA exonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4oke, PDBe:4oke, PDBj:4oke
PDBsum4oke
PubMed24704253
UniProtP9WJ73|EXRBN_MYCTU 3'-5' exoribonuclease Rv2179c (Gene Name=Rv2179c)

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