Structure of PDB 4oj8 Chain A

Receptor sequence
>4oj8A (length=253) Species: 555 (Pectobacterium carotovorum subsp. carotovorum) [Search protein sequence]
SEIVKFNPVMASGFGAYIDHRDFLEAKTETIKNLLMRQGFVVVKNLDIDS
DTFRDIYSAYGTIVEYVGFGYRDTLKLEGEKGKIVTGRGQLPFHADGGLL
LSQVDQVFLYAAEIKNVKFRGATTVCDHALACQEMPAHLLRVLEEETFEV
RVLWFKVPVFTDLGWVRKMLIYFPFDEGQPASWEPRIVGFTDHETQAFFQ
ELGAFLKQPRYYYKHFWEDGDLLIMDNRRVIHEREEFNDDDIVRRLYRGQ
TAD
3D structure
PDB4oj8 Mechanism of the C5 stereoinversion reaction in the biosynthesis of carbapenem antibiotics.
ChainA
Resolution2.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.14.20.3: (5R)-carbapenem-3-carboxylate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE2 A H101 D103 H251 H94 D96 H232
BS02 AKG A L84 L98 H101 H251 R253 R263 L265 R267 L77 L91 H94 H232 R234 R244 L246 R248
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0017000 antibiotic biosynthetic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4oj8, PDBe:4oj8, PDBj:4oj8
PDBsum4oj8
PubMed24604200
UniProtQ9XB59|CARC_PECCC (5R)-carbapenem-3-carboxylate synthase (Gene Name=carC)

[Back to BioLiP]