Structure of PDB 4oi7 Chain A

Receptor sequence
>4oi7A (length=211) Species: 9606 (Homo sapiens) [Search protein sequence]
AQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEAWKVLSPQGGGPW
DSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQIPG
KPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVS
VKEQTRRHPETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRT
APIQPRVWEPV
3D structure
PDB4oi7 RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
ChainA
Resolution3.104 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A K37 K39 K15 K17
BS02 dna A R29 R216 H217 R218 R7 R194 H195 R196
External links
PDB RCSB:4oi7, PDBe:4oi7, PDBj:4oi7
PDBsum4oi7
PubMed24081950
UniProtQ15109|RAGE_HUMAN Advanced glycosylation end product-specific receptor (Gene Name=AGER)

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