Structure of PDB 4ofm Chain A

Receptor sequence
>4ofmA (length=205) Species: 51031 (Necator americanus) [Search protein sequence]
VHYKLTYFAIRGAGECARQIFALADQEFEDVRLDKEQFAKVKPDLPFGQV
PVLEVDGKQLAQSLAICRYLARQFGFAGKSTFDEAVVDSLADQYSDYRVE
IKSFFYTVIGMREGDVEQLKKEVLLPARDKFFGFITKFLKKSPSGFLVGD
SLTWVDLLVSEHNATMLTFVPEFLEGYPEVKEHMEKIRAIPKLKKWIETR
PETLF
3D structure
PDB4ofm Structure of glutathione S-transferase 1 from the major human hookworm parasite Necator americanus (Na-GST-1) in complex with glutathione.
ChainA
Resolution2.64 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) Y8 A14 R19 V109
Catalytic site (residue number reindexed from 1) Y7 A13 R18 V108
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH A Y8 F39 Q50 V51 Q63 S64 Y7 F38 Q49 V50 Q62 S63
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity
Biological Process
GO:0006749 glutathione metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4ofm, PDBe:4ofm, PDBj:4ofm
PDBsum4ofm
PubMed25195885
UniProtD3U1A5

[Back to BioLiP]